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Publicaciones

  1. Ahumada, K., Urrutia, P., Illanes, A., Wilson, L., Production of combi-CLEAs of glycosidases utilized for aroma enhancement in wine; Food and Bioproducts Processing, 94:555-560, 2015
  2. Bernal, C., Illanes, A., Wilson, L., Improvement of Efficiency in the Enzymatic Synthesis of Lactulose Palmitate; Journal of Agricultural and Food Chemistry, 63(14):3716-3724, 2015
  3. Urrutia, P., Bernal, C., Escobar, S., Santa, C., Mesa, M., Wilson, L., Illanes, A., Influence of chitosan derivatization on its physicochemical characteristics and its use as enzyme support; Journal of Applied Polymer Science, 131(8), art. no. 40171, 2014
  4. Urrutia, P., Bernal, C., Wilson, L., Illanes, A., Improvement of chitosan derivatization for the immobilization of bacillus circulans β-galactosidase and its further application in galacto-oligosaccharide synthesis; Journal of Agricultural and Food Chemistry, 62(41):10126-10135, 2014
  5. Bernal, C., Illanes, A., Wilson, L., Heterofunctional hydrophilic-hydrophobic porous silica as support for multipoint covalent immobilization of lipases: Application to lactulose palmitate synthesis;Langmuir, 30(12):3557-3566, 2014
  6. Romero, O., Araya, E., Illanes, A., Wilson, L., Evaluation of kinetic parameters of immobilized penicillin G acylase subject to an inactivation and reactivation process; Journal of Molecular Catalysis B: Enzymatic, 104:70-74, 2014
  7. Santibáñez, L., Wilson, L., Illanes, A., Synthesis of ascorbyl palmitate with immobilized lipase from Pseudomonas stutzeri; JAOCS, Journal of the American Oil Chemists' Society, 91(3):405-410, 2014
  8. Bernal, C., Escobar, S., Wilson, L., Illanes, A., Mesa, M., Carbonaceous-siliceous composite materials as immobilization support for lipase from Alcaligenes sp.: Application to the synthesis of antioxidants; Carbon, 74, 2014
  9. Urrutia, P., Rodriguez-Colinas, B., Fernandez-Arrojo, L., Ballesteros, A.O., Wilson, L., Illanes, A., Plou, F.J. 
    , Detailed analysis of galactooligosaccharides synthesis with β-galactosidase from Aspergillus oryzae; Journal of Agricultural and Food Chemistry , 61 (5) , pp. 1081-1087, 2013
  10. Urrutia, P., Bernal, C., Escobar, S., Santa, C., Mesa, M., Wilson, L., Illanes, A., Influence of chitosan derivatization on its physicochemical characteristics and its use as enzyme support; Journal of Applied Polymer Science, 2013
  11. Bernal, C., Urrutia, P., Illanes, A., Wilson, L., Hierarchical meso-macroporous silica grafted with glyoxyl groups: Opportunities for covalent immobilization of enzymes; New Biotechnology, 30(5):500-506, 2013
  12. Urrutia, P., Mateo, C., Guisan, J.M., Wilson, L., Illanes, A., Immobilization of Bacillus circulans β-galactosidase and its application in the synthesis of galacto-oligosaccharides under repeated-batch operation; Biochemical Engineering Journal, 77:41-48, 2013
  13. Wilson, L., Illanes, A., Romero, O., Effect of inactivation and reactivation conditions on activity recovery of enzyme catalysts 
    ;     Electronic Journal of Biotechnology, 16(3), 2013
  14. Bahamondes, C., Wilson, L., Aguirre, C., Illanes, A. , Comparative study of the enzymatic synthesis of cephalexin at high substrate concentration in aqueous and organic media using statistical model.; Biotechnology and Bioprocess Engineering, 17:711-721, 2012
  15. Illanes, A., Cauerhff, A., Wilson, L., Castro, G. , Recent trends in biocatalysis engineering;Bioresource Technology, 115:48-57, 2012
  16. Pizarro, C., Brañes, M., Markovits, A., Fernández-Lorente, G., Guisán, J. M., Chamy, R., Wilson, L. , Influence of different immobilization techniques for Candida cylindracea lipase on its stability and fish oil hydrolysis ; Journal of Molecular Catalysis B: Enzmatic, 78: 111-118, 2012
  17. Romero, O., Guisán, J.M., Illanes, A., Wilson, L. , Reactivation of penicillin acylase biocatalysts: Effect of the intensity of enzyme–support attachment and enzyme load; Journal of Molecular Catalysis B: Enzymatic, 74:224-229, 2012
  18. Valencia, P., Flores, S., Wilson, L., Illanes, A. , Batch reactor performance for the enzymatic synthesis of cephalexin: Influence of catalyst enzyme loading and particle size.; New Biotechnology, 29:218-226, 2012
  19. Miranda, V., Wilson, L., Cárdenas, C., Illanes, A., Reactivation of immobilized penicillin G acylase: Influence of cosolvents and catalytic modulators. ; Journal of Molecular Catalysis B: Enzymatic., 68: 77-82, 2011
  20. Huerta, L.M., Vera, C., Guerrero, C., Wilson, L., Illanes, A., Synthesis of galacto-oligosaccharides at very high lactose concentrations with immobilized β-galactosidases from Aspergillus oryzae;Process Biochemistry 46 (1) , pp. 245-252 , 2011
  21. Valencia, P., Flores, S., Wilson, L., Illanes, A., Effect of Internal Diffusional Restrictions on the Hydrolysis of Penicillin G: Reactor Performance and Specific Productivity of 6-APA with Immobilized Penicillin Acylase ; Applied Biochemistry and Biotechnology , 1-16, 2011
  22. Valencia, P., Flores, S., Wilson, L., Illanes, A., Effect of particle size distribution on the simulation of immobilized enzyme reactor performance; Biochemical Engineering Journal, 49: 256-263. , 2010
  23. Valencia, P., Wilson, L., Aguirre, C., Illanes, A., Evaluation of the incidence of diffusional restrictions on the enzymatic reactions of hydrolysis of penicillin G and synthesis of cephalexin;Enzyme and Microbial Technology, 47: 268-276, 2010
  24. Illanes, A., González, J.M., Gómez, J.M., Valencia, P., Wilson, L., Diffusional restrictions in glyoxyl-agarose immobilized penicillin G acylase of different particle size and protein loading;Electronic Journal of Biotechnology , 13 (1) , 2010
  25. Illanes, A., Wilson, L., Aguirre, C. , Synthesis of Cephalexin in Aqueous Medium with Carrier-bound and Carrier-free Penicillin Acylase Biocatalysts.; Appl. Biochem. Biotechnol., 157(1):98-110., 2009
  26. Wilson, L., Illanes, A., Soler, L., Henríquez, M.J., Effect of the degree of cross-linking on the properties of different CLEAs of penicillin acylase; Process Biochemistry. , 44(3): 322-326, 2009
  27. Cea, G., Wilson, L., Bolívar, J.M., Markovits, A., Illanes, A., Effect of chain length on the activity of free, immobilized alcohol dehydrogenase towards aliphatic alcohols; Enzyme and Microbial Technology, 44 (3): 135-138., 2009
  28. Rodrigues, R., Godoy,C., Filice, M., Bolivar, J.M., Palau-Ors, A., Garcia-Vargas,J.M., Romero, O., Wilson, L., Ayub, M., Fernandez-Lafuente, R., Guisan, J.M. , Reactivation of covalently immobilized lipase from Thermomyces lanuginosus; Process Biochemistry, 44 (6): 641-646, 2009
  29. Romero, O., Vergara, J., Fernández-Lafuente, R., Guisán, J.M., Illanes, A., Wilson, L., Simple strategy of reactivation of a partially inactivated penicillin g acylase biocatalyst in organic solvent and its impact on the synthesis of beta-lactam antibiotics; Biotechnol Bioeng, 103(3):472-9, 2009
  30. Wilson, L., Illanes, A., Romero, O., Vergara, J., Mateo, C. 
    , Carrier-bound and carrier-free penicillin acylase biocatalysts for the thermodynamically controlled synthesis of β-lactam compounds in organic medium. 
    ;     Enzyme and Microbial Technology 43 (6), 442-447, 2008
  31. Illanes, A., Wilson, L., Altamirano, C., Cabrera, Z., Alvarez, L., Aguirre, C. , Enzyme and Microbial , 40: 195-203, 2007
  32. Bolivar, J.M., Wilson, L., Ferrarotti, S.A., Fernandez-Lafuente, R., Guisán, J.M., Mateo, C., Enzyme and Microbial Technology , 40: 540-546, 2007
  33. Illanes, A., Wilson, L., Corrotea, O., Tavernini, L., Zamorano, F., Aguirre, C., Journal of Molecular Catalysis. B. Enzymatic , 47(1-2): 72-78, 2007
  34. Illanes, A., Wilson, L., Corrotea, O., Tavernini, L., Aguirre, C. 
    , Journal of Biotechnology , 131: S74, 2007
  35. Wilson, L., Romero, O., Vergara, J., Illanes, A., Journal of Biotechnology, 131: S92, 2007
  36. Illanes, A., Wilson, L., Caballero, E., Fernández-Lafuente, R., Guisán, J.M. , Cross-linked penicillin acylase aggregates for the synthesis of b-lactam antibiotics in organic medium. ; Appl. Biochem. Biotechnol. , 133:189-202, 2006
  37. Wilson, L., Fernández-Lorente, G., Fernández-Lafuente, R., Illanes, A., Guisán J.M., Palomo, J.M. , CLEAs of lipases and poly-ionic polymers: A simple way of preparing stable biocatalysts with improved properties. ; Enzyme and Microbial Technology. , 39:750-755, 2006
  38. Bolivar, J.M., Wilson, L., Ferrarotti, S.A., Fernández-Lafuente, R., Guisán, J.M., Mateo, C. ,Stabilization of a formate dehydrogenase by covalent immobilization on highly activated glyoxyl-agarose supports. ; Biomacromolecules., 7(3):669-73, 2006
  39. Bolivar, J.M., Wilson, L., Ferrarotti, S.A., Guisán, J.M., Fernández-Lafuente,R., Mateo, C. ,Improvement of the stability of alcohol dehydrogenase by covalent immobilization on glyoxyl-agarose. ; J. Biotechnol. , 125:85-94, 2006
  40. Wilson, L., Palomo, J.M., Fernández-Lorente, G., Illanes, A., Guisán J.M., Fernández-Lafuente, R., Improvement of the functional properties of a thermostable lipase from Alcaligenes sp. via strong adsorption on hydrophobic supports. ; Enzyme and Microbial Technology. , 38: 975-980, 2006
  41. Illanes, A., Wilson, L., Altamirano, C., Cabrera, Z., Alvarez, L., Aguirre, C. , Production of cephalexin in organic medium at high substrate concentrations with CLEA of penicillin acylase and PGA-450. ; Enzyme and Microbial Technology. In Press. , 2006
  42. Wilson, L., Palomo, J.M., Fernández-Lorente, G., Illanes, A., Guisán J.M., Fernández-Lafuente, R. , Improvement of the functional properties of a thermostable lipase from Alcaligenes sp. via strong adsorption on hydrophobic supports. ; Enzyme and Microbial Technology , 38: 975-980, 2006
  43. Bolivar, J.M., Wilson, L., Ferrarotti, S.A., Fernandez-Lafuente, R., Guisan, J.M., Mateo, C. ,Evaluation of different immobilization strategies to prepare an industrial biocatalyst of formate dehydrogenase from Candida boidinii. ; Enzyme and Microbial Technology. , In Press, 2006
  44. Ferrarotti, S.A., Bolivar, J.M., Mateo, C., Wilson, L., Guisán, J.M., Fernández-Lafuente, R. ,Immobilization and stabilization of a cyclodextrin glycosyltransferase by covalent attachment on highly activated glyoxyl-agarose supports. ; Biotechnol Prog, 22(4):1140-1145, 2006
  45. Illanes A., Wilson L. , Kinetically-controlled synthesis of b-lactam antibiotics. ; Chimica Oggi/ Chemistry Today , 24(5): 27-30, 2006
  46. Illanes, A., Wilson, L., Caballero, E., Fernández-Lafuente, R., Guisán, J.M., Cross-linked penicillin acylase aggregates for the synthesis of b-lactam antibiotics in organic medium. ; Appl. Biochem. Biotechnol., 133:189-202, 2006
  47. Mateo, C., Abian, O., Grazú, V., Fernández-Lorente, G., Palomo, J.M., Fuentes, M., Segura, R., Montes, T., López-Gallego, F., Wilson, L., Torres, R., Guisán, J.M., Fernández-Lafuente, R. , Recent advances in enzymatic industrial synthesis of semi-synthetic b-lactam antibiotics. ; 2: 207-218, 2005
  48. Wilson, L., Palomo, J.M., Fernández-Lorente, G., Illanes, A., Guisán J.M., Fernández-Lafuente, R. , Effect of lipase–lipase interactions in the activity, stability and specificity of a lipase from Alcaligenes sp. ; Enzyme and Microbial Technology, 39:259-264, 2005
  49. Wilson, L., Illanes, A., Abián O., Pessela, B., Fernández-Lafuente, R., Guisán, J.M. , Co-aggregation of penicillin g acylase and polyionic polymers: an easy methodology to prepare enzyme biocatalysts stable in organic media. ; Biomacromolecules, 5: 852-857, 2004
  50. Wilson, L., Illanes, A., Pessela, B., Abian, O., Fernández-Lafuente, R., Guisán, J.M. ,Encapsulation of Cross-Linked Penicillin G Acylase Aggregates in LentiKats®. Evaluation of a novel biocatalyst in organic media. ; Biotechnol Bioeng. , 86: 558-562, 2004
  51. Wilson, L., Betancor, L., Fernandez-Lorente, G., Fuentes, M., Hidalgo, A., Guisan, J.M., Pessela, B.C., Fernandez-Lafuente, R. , Cross-linked aggregates of multimeric enzymes: a simple and efficient methodology to stabilize their quaternary structure. ; Biomacromolecules. , 5: 814-817, 2004
  52. Illanes, A., Wilson, L. , Diseño de Reactores Enzimáticos bajo Condiciones de Inactivación en Reactores Enzimáticos, Tópicos en Biotecnología (Ed. Dr. Sergio Huerta Ochoa). ; Ed. Universidad Autónoma Metropolitana, México D.F., Primera edición, 2004
  53. Illanes, A., Cabrera, Z., Wilson,L., Aguirre, C. , Synthesis of cephalexin in ethylene glycol with glyoxyl-agarose immobilised penicillin acylase: temperature and pH optimisation. 

    ;     Process Biochemistry, 39: 111-117, 2003
  54. Illanes, A., Wilson, L. , Enzyme reactor design under thermal inactivation. 
    ;     Crit Rev Biotechnol. , 23: 61-93, 2003
  55. Wilson, L., Illanes, A., Abián, O., Fernandez-Lafuente, R., Guisán, J.M., Encapsulation of very soft cross-linked enzyme aggregates (CLEAs) in very rigid LentiKats (TM). ; Landbauforsch Völkenrode, 241:121-125, 2002
  56. Abián, O., Wilson, L., Mateo, C., Fernández–La Fuente, G., Palomo, J.M., Fernández–La Fuente, R., Guisán, J.M., J.M. Preparation of artificial hyper-hydrophilic micro-environments(polymeric salts) surrounding enzyme molecules. New enzyme derivates to be used in any reaction medium. ; J. Mol Cat B: Enzymatic. , 19: 295-303, 2002
  57. A.Illanes, A., Wilson, L., Tomasello, G. , Effect of modulation on enzyme inactivation on temperature optimization for reactor operation with chitin-immobilized lactase. ; J. Molec. Catal. B. Enzymatic. , 11. 531-540, 2001
  58. Illanes, A., Wilson, L., Tomasello, G., Temperature optimization for reactor operation with with chitin-immobilized lactase under modulated inactivation. ; Enzyme Microb. Technol. , 27:270-278, 2000

Libros y capítulos de libros

  1. Illanes, A., Vera, C., Wilson, L., Problem Solving in Enzyme Biocatalysis; Wiley, United Kingdom, 2014
  2. Illanes, A., Wilson, L., Zamorano F., Aguirre, C., Journal of Biotechnology, 131:, S74, 2007
  3. Bolivar, JM., Wilson L., Ferroatti S.A., Guisán J.M., Fernández-Lafuente,R., Mateo, C. J. , Journal of Molecular Catalysis B: Enzymatic 
    ;     Biotechnol. , 125:85-94, 2006
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